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» Scientific References » Toxicology & Other Health Benefits

Toxicology & Ohter Health Benefits



2007
Norazlina M, Lee PL, Lukman HI, Nazrun AS, Ima-Nirwana S. (2007) Effects of vitamin E supplementation on bone metabolism in nicotine-treated rats. Singapore Medical Journal 48(3):195-9.

Franke AA, Murphy SP, Lacey R, Custer LJ. (2007)
 Tocopherol and tocotrienol levels of foods consumed in Hawaii.
Journal of Agricultural & Food Chemistry 55(3):769-78.

2006

Sen CK, Khanna S, Roy S (2006) Tocotrienols: Vitamin E beyond tocopherols. Life Sciences 78(18):2088-98.

Singh VK, Shafran RL, Jackson WE 3rd, Seed TM, Kumar KS (2006) Induction of cytokines by radioprotective tocopherol analogs. Experimental and Molecular Pathology 81(1): 55-61.

2005

Azlina MF, Nafeeza MI, Khalid BA (2005) A comparison between tocopherol and tocotrienol effects on gastric parameters in rats exposed to stress. Asia Pacific Journal Clinical Nutrition 14(4): 358-65.

Esterhuyse AJ, Toit ED, Rooyen JV (2005) Dietary red palm oil supplementation protects against the consequences of global ischemia in the isolated perfused rat heart. Asia Pacific Journal Clinical Nutrition 14(4): 340-7.

Anderson SL, Rubin BY (2005) Tocotrienols reverse IKAP and monoamine oxidase deficiencies in familial dysautonomia. Biochemical and Biophysical Research Communications 336(1): 150-6.

Nafeeza MI, Kang TT (2005) Synergistic effects of tocopherol, tocotrienol, and ubiquinone in indomethacin-induced experimental gastric lesions. International Journal for Vitamin and Nutrition Research 75(2): 149-55.

Meyenberg A, Goldblum D, Zingg JM, Azzi A, Nesaretnam K, Kilchenmann M, Frueh BE (2005) Tocotrienol inhibits proliferation of human Tenon's fibroblasts in vitro: a comparative study with vitamin E forms and mitomycin C. Graefe's Archive for Clinical and Experimental Ophthalmology 243(12): 1263-71.

2004

Cespedes CL, Torres P, Marin JC, Arciniegas A, Romo de Vivar A, Perez-Castorena AL, Aranda E (2004) Insect growth inhibition by tocotrienols and hydroquinones from Roldana barba-johannis. Phytochemistry 65(13): 1963-75.

Zhou C, Tabb MM, Sadatrafiei A, Grun F, Blumberg B (2004) Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metabolism and Disposition 32(10):1075-82.

Ima-Nirwana S, Suhaniza S (2004) Effects of tocopherols and tocotrienols on body composition and bone calcium content in adrenalectomized rats replaced with dexamethasone. Journal of Medicinal Food 7(1): 45-51.

Anderson SL, Qiu J, Rubin BY (2003) Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia. Biochemical and Biophysical Research Communications 306(1): 303-9.

2003

Iqbal J, Minhajuddin M, Beg ZH (2003) Suppression of 7,12-dimethylbenz[alpha]anthracene- induced carcinogenesis and hypercholesterolaemia in rats by tocotrienol-rich fraction isolated from rice bran oil. European Journal of Cancer Prevention 12(6):447-53.

Anderson SL, Qiu J, Rubin BY (2003) Tocotrienols induce IKBKAP expression: a possible therapy for familial dysautonomia. Biochemical and Biophysical Research Communications 306(1):303-9.

Saito H, Kiyose C, Yoshimura H, Ueda T, Kondo K, Igarashi O (2003) γ-Tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor. Journal of Lipid Research 2003 44:1530-35.


Cahoon EB, Hall SE, Ripp KG, Ganzke TS, Hitz WD, Coughlan SJ (2003) Metabolic redesign of vitamin E biosynthesis in plants for tocotrienol production and increased antioxidant content. Nature Biotechnology 21(9):1082-7.


Norazlina M, Ima-Nirwana S, Abul Gapor MT, Abdul Kadir Khalid B. (2003) Tocotrienols are needed for normal bone calcification in growing female rats. Asia Pac J Clin Nutr 2002;11:194-199.

2002

Wan Nazaimoon WM, Khalid BA (2002) Tocotrienols-rich diet decreases advanced glycosylation end-products in non-diabetic rats and improves glycemic control in streptozotocin-induced diabetic rats. Malaysian Journal of Pathology 24(2): 77-82.

Nafeeza MI, Fauzee AM, Kamsiah J, Gapor MT (2002) Comparative effects of a tocotrienol-rich fraction and tocopherol in aspirin-induced gastric lesions in rats. Asia Pacific Journal Clinical Nutrition 11(4): 309-13.

van Haaften RI, Haenen GR, Evelo CT, Bast A (2002) Tocotrienols inhibit human glutathione S-transferase P1-1. IUBMB Life 54(2): 81-4.

Norazlina M, Ima-Nirwana S, Abul Gapor MT, Abdul Kadir Khalid B (2002) Tocotrienols are needed for normal bone calcification in growing female rats. Asia Pacific Journal Clinical Nutrition 11(3): 194-9.

Nakamura H, Furukawa F, Nishikawa A, Miyauchi M, Son HY, Imazawa T, Hirose M (2001) Oral toxicity of a tocotrienol preparation in rats. Food and Chemical Toxicology 39(8): 799-805.

1999

Gu JY, Wakizono Y, Sunada Y, Hung P, Nonaka M, Sugano M, Yamada K (1999) Dietary effect of tocopherols and tocotrienols on the immune function of spleen and mesenteric lymph node lymphocytes in Brown Norway rats. Bioscience, Biotechnology and Biochemistry 63(10): 1697-702.

1997

Thiele JJ, Traber MG, Podda M, Tsang K, Cross CE, Packer L (1997) Ozone depletes tocopherols and tocotrienols topically applied to murine skin. FEBS Letters 401(2-3): 167-70.

1995

Jarvinen R (1995) Carotenoids, retinoids, tocopherols and tocotrienols in the diet; the Finnish Mobile Clinic Health Examination Survey. International Journal for Vitamin and Nutrition Research 65(1): 24-30.

1992

Babu US, Jenkins MY, Mitchell GV (1992) Effect of short-term feeding of barley oil extract containing naturally occurring tocotrienols on the immune response of rats. Annals of the New York Academy of Sciences 669: 317-9.

Koba K, Abe K, Ikeda I, Sugano M (1992) Effects of alpha-tocopherol and tocotrienols on blood pressure and linoleic acid metabolism in the spontaneously hypertensive rat (SHR). Bioscience, Biotechnology and Biochemistry 56(9): 1420-3.

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» Antioxidant Activity
» Cholesterol Reduction
» Cardiovascular Health & Protection
» Cancer Prevention - Breast Cancer
» Cancer Prevention - Liver Cancer
» Anti-Cancer - General
» Anti-Aging
» Neuroprotective Property
» Distribution & Bioavailability


   
 
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